Tweet 1: I can see a lot of people either avoiding Plan B & ending up pregnant or attempting to take multiple doses & getting sick.
Tweet 2: anyone w a credit card (not everyone, I know) can/should use ella ella-rx.com they’ll ship it overnight $45
SIGNAL BOOST. Ella is another form of emergency contraception/the morning-after pill. It’s more effective than Plan B and can be taken up to FIVE DAYS after your mishap, rather than three days. Please spread this around; with all of the anti-choice legislation flying about and how difficult it can be for some people to get Plan B even OTC (like minors, people living in small towns, etc.), this might be the only way a lot of people can get their hands on the morning-after pill.
I’ve also read that Ella is more effective for plus size people.
This is important. Ella works for everyone. Plan B is not effective for people over 176 pounds. Protect yourself
Actually, everyone might want to do a little more research on this one. It looks like Ella has a similar issue for overweight people. Someone with a better head than mine for reading scientific material should read the FDA material, but this is what I’m seeing:
Subgroup analysis of the pooled data by BMI showed that for women with BMI > 30 kg/m, the observed pregnancy rate was 3.1% (95% CI: 1.7, 5.7), which was not significantly reduced compared to the expected pregnancy rate of 4.5% in the absence of emergency contraception taken within 120 hours after unprotected intercourse.
In the comparative study, a similar effect was seen for the comparator emergency contraception drug, levonorgestrel 1.5 mg. For levonorgestrel, when used by women with BMI > 30 kg/m2, the observed pregnancy rate was 7.4% (95% CI: 3.9, 13.4), compared to the expected pregnancy rate of 4.4% in the absence of emergency contraception taken within 72 hours after unprotected intercourse.
Bolding is mine. Levonorgestrel is Plan-B. A BMI of 30 is considered “moderately obese.”
It says point blank in the label materials, “ella and other emergency contraceptives may be less effective in women with a body mass index (BMI) > 30 kg/m2.”
Petra is quite correct. I do have a couple of remarks to add for people to consider (because I’m a loud mouth).
1) The non significant reduction results comes from the manufacturer (who I am inclined to believe due to their vested interest). However, that means we don’t have access to their methods and analyses to see what they did and therefore be able to analyse their methods
1a) For example I don’t know how they decided that 4.5% was the pregnancy rate in those who did not take EC, especially when their expected pregnancy rate in their populations were 5.5 and 5.6. Which, after doing some quick and dirty statistics, if they used those rates they could say they are 90% confident that Ella reduces pregnancy in heavier women. So yeah, no idea where that came from. They could have a very good reason to chose that rate (maybe it’s an industry standard) but I don’t know what it is.
2) Some of the studies I’ve seen had a rather low number of heavier women who became pregnant, meaning results are very imprecise and power is lower.
3) All evidence supports a higher risk of EC failure (no matter the drug) in overweight and obese women
4)Studies supports that Ella (Ulpristal acetate) is more effective than Plan B (Levonorgestrel) in reducing pregnancies in heavier women.
5) Levonorgestrel had even worse rates of pregnancies among heavier women. 7.4%(95% CI: 3.9, 13.4) with an expected pregnancy rate of 4.4% <-again don’t know where that number came from.
Take away points:
1) If you are heavier and need EC, Ella is your best bet but you should go in knowing that there it may fail. (But hey, if you need EC, it’s more likely to work than Levonorgestrel).
2) More studies are needed to research this area of EC failure so that we may have a better idea of its effectiveness in heavier women.
3) If you are heavier and sexually active, (finances allowing, of course) consider hormonal birth control or a copper IUD (IUDs being extremely effective and reversible).